One Sleepless Night Alters the Immune System and Triggers Inflammation

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Sleep disorders are associated with various chronic conditions including diabetes and heart diseases.

A single sleep night can greatly affect the immune system, even in young, healthy and lean individuals. According to a new study, sleep deficiency is similar to people found in obese individuals. Research published in the journal of immunology and reported by Medical Express, describes how the quality of sleep affects the potential link of immune function and conditions such as obesity, diabetes and heart disease.

Sleep and chronic inflammation


There are enough evidence connecting sleep disorders to many chronic diseases including type 2 diabetes and heart disease. Chronic inflammation is often at the root of these health issues. However, the direct effect of sleep on immune cells in the bloodstream, especially monocytes, is less discovered.

Monocytes play an important role in the body’s natural immune protection, detect pathogens and trigger immune reactions. There are three main types of monocytes: classical, transitional and non-classical. Non-classical monocytes patrol the body, respond to inflammatory signs, and help regulate immune reactions.

Researchers at the Dasman Diabetes Institute in Kuwait analyzed sleep patterns and blood samples with a separate body mass index (BMI) from 237 healthy adults. He examined monocyte levels and inflammatory markers to understand the relationship between sleep quality, immune function and inflammation.

Major findings


Published on 24 February in the Journal of Immunology, the study found that the quality of sleep was quite poorly compared to lean participants in obese individuals and more prone to the inflammation of the old-grain. Thick individuals also had a higher number of non-classical monocytes, which was correlated with poor sleep and elevated inflammatory markers.

Most of the striking, researchers found that even in lean individuals, only one night of sleep deficiency was enough to change the immune cell profile, making them similar to the people found in obesity. This suggests that the immune system is highly sensitive to gold and quickly suited to disruptions in the gold cycle. Constant sleep disturbances can contribute to long -term inflammation and increase the risk of the disease.

“Our findings highlight a growing public health concern,” the lead researcher Dr. Fatima Rashid said. “With progress in technology, screen time increases, and to move social norms, sleep patterns are being rapidly disrupted – leading to serious consequences for immune function and overall health.”

Future research and solutions


Researchers aim to check the lack of sleep and the biological mechanism connecting immune changes. They also expect to determine whether these effects can be reversed through guidelines on structured sleep remedies or technology use.

“Our long -term goal is to use this research as a foundation for policies and strategies that recognize the required role of sleep. We imagine workplace adjustment and public awareness campaigns promoting better sleep habits, especially for high risk persons of sleep deficiency due to business or technical factors, ”Dr. Rashid said. “Finally, improvement of sleep can help reduce the burden of inflammatory diseases

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